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In a detailed survey covering side effects associated with glucocorticoids in 226 patients with adrenal insufficiency, the percentage of sleep-related difficulties—particularly trouble falling asleep—was found to be: • 25% among participants with congenital adrenal hyperplasia (CAH), • 27% among those with hypopituitarism, • 48% among those with Addison’s disease. A common practice in endocrinology is that the last dose of hydrocortisone should be given no later than 6:00 p.m. (18:00). This rais
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