How do you pick against Patrick Mahomes in the biggest game of the year? You don't. That's the simple way to make a pick for Super Bowl LIX. When the Kansas City Chiefs and Philadelphia Eagles take the field Sunday at the Caesars Superdome,

Mahomes has been dealing with an ankle injury, but it did not affect his ability to lead the Chiefs to a win over the Buffalo Bills in the AFC Championship Game last month. Mahomes is still listed with an ankle injury after Kansas City’s Super Bowl bye week, but he was a full participant in the Chiefs’ practice session on Wednesday.