San Francisco 49ers linebacker Fred Warner will be on ESPN's 'Manningcast' broadcast for Chiefs vs. Jaguars on Monday night.

Dealing with a laundry list of injuries to the defensive line, the 49ers held tryouts Tuesday with seven defensive linemen, ...

49ers GM John Lynch comments on potential trade possibilities amid Nick Bosa’s injury originally appeared on The Sporting ...

The San Francisco 49ers have gone 3-0 with Mac Jones and 1-1 with Brock Purdy, and now some are asking if the team should ...

NFL Week 6 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers and Tampa Bay Buccaneers.

ESPN breaks down the top 5 NFL overreactions, including the Patriots’ shocking playoff buzz, the 49ers’ dominant return, and ...

San Francisco 49ers quarterback Brock Purdy is officially out for "Thursday Night Football" against the Los Angeles Rams with ...

An ESPN analyst believes former Alabama quarterback Mac Jones would be an elite NFL signal-caller if he wasn't drafted by the ...

Those who wanted the Los Angeles Rams and San Francisco 49ers to battle in a high-scoring NFC West matchup in Week 5 may be ...

Christian McCaffrey was fined $23,186 for using his helmet on a tackle attempt vs. the Jaguars, per Tom Pelissero.

The 49ers will re-evaluate Brock Purdy’s sore toe from Sunday’s loss to the Jaguars and with a Thursday game fast approaching ...

However, they’ve avoided the injury to their star running back that had everyone worried to start the year, but in a crucial ...