San Francisco 49ers linebacker Fred Warner will be on ESPN's 'Manningcast' broadcast for Chiefs vs. Jaguars on Monday night.

The Packers are massive favorites over the Bengals, while Lions-Chiefs is among games with the highest totals.

Dealing with a laundry list of injuries to the defensive line, the 49ers held tryouts Tuesday with seven defensive linemen, ...

49ers GM John Lynch comments on potential trade possibilities amid Nick Bosa’s injury originally appeared on The Sporting ...

The San Francisco 49ers have gone 3-0 with Mac Jones and 1-1 with Brock Purdy, and now some are asking if the team should ...

Jones has thus far gone 3-0 as San Francisco's temporary QB1, and he seems to be on track to start this coming Sunday's game ...

In Sunday's late afternoon window, the Tampa Bay Buccaneers host the San Francisco 49ers in a matchup of 4-1 teams and the ...

ESPN breaks down the top 5 NFL overreactions, including the Patriots’ shocking playoff buzz, the 49ers’ dominant return, and ...

San Francisco 49ers quarterback Brock Purdy is officially out for "Thursday Night Football" against the Los Angeles Rams with ...

An ESPN analyst believes former Alabama quarterback Mac Jones would be an elite NFL signal-caller if he wasn't drafted by the ...

Those who wanted the Los Angeles Rams and San Francisco 49ers to battle in a high-scoring NFC West matchup in Week 5 may be ...

INGLEWOOD, Cali. -- The Los Angeles Rams face the San Francisco 49ers in a NFL Week 5 matchup on Thursday. Our two team ...