Just as the growing interest and proliferation of methods to reperfuse the coronary artery system with transcatheter techniques spurred interest and utilization of intracoronary ultrasound (at least ...

Graduate Program in Translational Biology, Medicine, and Health (R.L.P., G.A.B., K.E.S., D.R.K.), Virginia Tech, Blacksburg. Fralin Biomedical Research Institute at ...

Background and Purpose— White matter lesions (WMLs) have been shown to be associated with the risk of stroke in previous studies but little is known about the prediction of other vascular events. We ...

In 2004, Joseph Loscalzo, the then-new editor-in-chief of Circulation, invited readers to use the journal to soar like an eagle above the cardiovascular landscape and to stay informed of cutting-edge ...

4. Choosing the Right Pathway With Patient-Centric Algorithms for Acute Chest Pain e343 4.1. Patients With Acute Chest Pain and Suspected Acute Coronary Syndrome (Not Including STEMI) e343 4.1.1.

The present document is a comprehensive guideline statement on the management of patients with acute ischemic stroke that supercedes the prior statement and interim updates. 1–3 These guidelines have ...

Changes in left ventricular (LV) diastolic pressure after transcatheter aortic valve replacement (TAVR) or their relationship with subsequent outcomes remain poorly clarified. Accordingly, we aimed to ...

In cardiovascular tissues and, likely the lung, an important role of the SODs is to protect NO against oxidative inactivation by superoxide. Both NO and superoxide are free radicals with unpaired ...

Background— Although both sirolimus (CYPHER) and paclitaxel (TAXUS) drug-eluting stents have demonstrated efficacy and safety in clinical trials, human autopsy data have raised concerns about ...

Platelet–neutrophil interactions play a key role in cardiovascular disease and inflammatory processes. Src family kinases mediate P-selectin glycoprotein ligand-1–Mac-1 cross talk necessary for firm ...

A paucity of data exists on mitral valve (MV) deformation during the cardiac cycle in man. Real-time 3-dimensional (3D) echocardiography now allows dynamic volumetric imaging of the MV, thus enabling ...