A model of the genome is described which relates certain observations on the additive nature of enzyme activity to observations on the quantitative genetics of fitness traits. The model assumes that ...

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system. Enzymes usually clear these nucleic acids before they cause an issue, but when these ...

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism. Lipoprotein-associated phospholipase A 2 (Lp-PLA 2) is ...

All living things are made of carbon, and sugars, e.g. glucose, are a very common source of it. Consequently, most cells are good at eating sugars, using enzymes to digest them through a series of ...

R. L. Sinsabaugh, R. K. Antibus, A. E. Linkins, C. A. McClaugherty, L. Rayburn, D. Repert and T. Weiland Because plant litter decomposition is directly mediated by ...

Studying mice and fruitflies, researchers found that the enzyme intestinal alkaline phosphotase helped prevent intestinal permeability and gut-derived systemic inflammation, resulting in less frailty ...

The muscle destruction associated with Duchenne muscular dystrophy (DMD), the most common childhood form of muscular dystrophy, is halted in mice when supplemental amounts of a naturally occurring ...