In an experiment comparing the effects of five different drugs, each drug is tested on a number of different subjects. The outcome of each experiment is the presence or absence of a positive response ...

This example analyzes the data from Beitler and Landis (1985), which represent results from a multi-center clinical trial investigating the effectiveness of two topical cream treatments (active drug, ...

Biometrika is primarily a journal of statistics in which emphasis is placed on papers containing original theoretical contributions of direct or potential value in applications. From time to time, ...

A method is proposed for obtaining approximate confidence intervals for the ratio of two binomial proportions based on two independent binomially distributed random variables. This method is compared ...