Safety is a major cause of attrition in drug discovery and development 1,2 and is, thus, a key consideration when making decisions at the major transition points in the drug pipeline (Box 1).

This reliance overlooks the fact that the underlying data may be weak or, in some instances, completely absent. In many low-resource environments, the lack of strong civil registration and vital ...

Theoretical models are at the base and their utility lies in exploring potential mechanisms and scenarios. Next are models fitted to observed data with internal validity checks, and above these are ...

Next Management said it is severing all remaining legal links with Faith Kates, adding her association with Epstein “was completely and absolutely unknown to Next management and its top executives,” ...