Take a look at the injury report for the San Francisco 49ers (5-2), which has 16 players listed (including Christian McCaffrey), as the 49ers prepare for their matchup versus the Houston Texans (2-4) at NRG Stadium, on Sunday, Oct. 26 at 1 p.m. ET.

SANTA CLARA, Calif. – Today, the San Francisco 49ers announced a new investment in the team by Pete Briger Jr. and the Briger family, who have acquired a non-controlling, minority interest in the team. The deal, which was approved by the NFL at the League meeting on October 22, will drive organizational growth and enable new opportunities.

Find single game tickets to the Houston Texans vs. San Francisco 49ers NFL Week 8 matchup on Sunday, October 26, 2025 at NRG Stadium.

QB Brock Purdy continues to work his way back as several key players sit out or are limited ahead of Sunday's Week 8 matchup vs. the Texans.