EXPORT MECHANISM: The tRNA must mature inside the nucleus before export. tRNAs are aminoacylated, and only tRNAs charged with an amino acid are exported efficiently. Export occurs when the tRNA is ...

This narrated animation illustrates the process of protein synthesis, starting with chromosomal DNA inside the cell's nucleus. A gene is transcribed into messenger RNA, which leaves the nucleus and ...

Scientists have uncovered key new information towards understanding the crucial first step in protein synthesis, the process by which the genetic code, harbored within DNA and copied into RNA, is ...

This is a preview. Log in through your library . Journal Information PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, ...

An international team of scientists have used advanced microscopy to image how ribosomes recruit to mRNA. Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell ...

Ribosome Assembly: New research shows that neurons not only synthesize proteins locally near synapses. They can also assemble ribosomes at synapses. Dynamic Regulation: Local ribosome maturation ...

A team of Yale researchers discovered how a protein called Ndc1 coordinates nuclear pore and envelope assembly after cell division, an important component of understanding how cell nuclei change in ...

Disease-causing huntingtin, shown in red, interacts with ribosomes, shown in green, in a striatal neuron. The nucleus is blue. [Nicolai Urban of Max Planck Institute for Neuroscience in Jupiter, ...

When a bone grows, our bodies’ proteins help provide the structure. When a muscle tears, proteins help rebuild it. When we fight an infection, transport oxygen in our blood or send messages to a cell, ...

NEW ORLEANS — Building muscle, nine essential amino acids (EAA) at a time, is the driving force behind muscle protein synthesis (MPS) – overcoming the normal effects of muscle protein breakdown (MPB) ...