The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer's disease (AD), ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

Scientists have uncovered how a newly discovered gene, NEK1, in which mutations have been linked to ALS cases, disrupts the function of the motor neuron and causes it to degenerate and die. The viral ...

Johns Hopkins Medicine neuroscientists say they have found a new function for the SYNGAP1 gene, a DNA sequence that controls memory and learning in mammals, including mice and humans. The finding, ...

Brian Cunniff, an assistant professor of pathology and laboratory medicine at the University of Vermont, will discuss how the subcellular positioning of mitochondria regulates gene-expression patterns ...

Researchers at the Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, and the University of Utah School of Medicine, have demonstrated that a gene therapy can ...

National University of Singapore (NUS) researchers have devised a method to safely and temporarily "switch off" and then "turn on" ribonucleic acid (RNA) inside cells. This is achieved using ...

The UB team that discovered how a gene found in 75% of us protects against neurodegeneration has now found that this same gene enhances immune function as well. The new findings were published in ...

Researchers at University of California San Diego School of Medicine have developed a gene therapy for Alzheimer’s disease that could help protect the brain from damage and preserve cognitive function ...