Animals depend on their sense of smell to locate food, identify mates and evade danger. In mammals, olfactory perception ...

Being abundant primary producers, single-celled eukaryotic diatoms and dinoflagellates dominate marine food webs and significantly impact the ecology of the oceans. These organisms face competition ...

G protein-coupled receptors (GPCRs) are seminal transducers of extracellular signals into intracellular responses, orchestrating intricate cascades that regulate cell proliferation, migration and ...

Galanin is a biologically active neuropeptide, and functions through three distinct G protein–coupled receptors (GPCRs), namely GALR1, GALR2, and GALR3. GALR signaling plays important roles in ...

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse ...

Single-cell proteogenomic analysis defined the lymphoma microenvironment as immune-inflamed, -deficient, and desert, in association with different setpoints of cancer-immunity cycle. EBV interacted ...

GPCRs are the largest receptor class, affecting almost every aspect of human physiology, with 35% of all approved drugs acting on GPCRs. They regulate sensory and neuronal signaling, as well as a ...

G protein-coupled receptors (GPCRs) are transmembrane proteins that transduce an extracellular signal—ligand binding—into an intracellular signal—activation of G-protein—which in turn activates ...

A publication from Acta Pharmaceutica Sinica B discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a debilitating ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments-water, lipid membranes, or other condensed phases-are critical to their ...