Technical Terms GPCR: A large family of cell surface receptors that respond to a variety of external signals, initiating intracellular signal transduction cascades.

G protein-coupled receptors (GPCRs) are essential for cell signal transduction and comprise the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple ...

GPCR structure: Research reveals molecular origins of function for a key drug target Date: December 31, 2023 Source: St. Jude Children's Research Hospital Summary: Scientists reveal how G protein ...