The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

DNA replication is a fundamental biological process that enables the accurate duplication of an organism’s genetic material. This intricate mechanism ensures that each new cell receives a complete set ...

A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

Many cancers harbor pro-proliferative mutations of the mitogen-activated protein kinase (MAPK) pathway. In BRAF-driven melanoma cells treated with BRAF inhibitors, subpopulations of cells escape ...