We wanted to find out if oral nicotine pouches can help people transition away from smoking, nicotine vaping, or other forms of tobacco use. We also wanted to know if oral nicotine pouches caused any ...

Epilepsy is a brain condition that causes seizures. It affects around one in 1000 children under five years old, and around one in 200 children between five and 19 years old. In a seizure, the brain's ...

The effect of oral riboflavin (vitamin B 2) supplements on blood pressure is uncertain. Large, well-conducted trials are needed to assess the effect of riboflavin on blood pressure lowering.

We do not know if medicinal and non-medicinal treatments help reduce impulsive-compulsive behaviors in people with Parkinson's disease because the currently available evidence is limited and uncertain ...

Simple hysterectomy may result in little to no difference in the number of deaths from any cause, life expectancy after treatment, deaths from cancer, cancer-free period after treatment, or the rate ...

Why systematic and rigorous searches are important, planning and designing search strategies, sources of studies, managing and reporting the process.

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Our Handbooks describe the process of preparing and maintaining diverse types of systematic reviews. Handbooks are updated regularly to reflect advances in systematic review methods and in response to ...

Growth of bacteria in the urine without any complaints (asymptomatic bacteriuria) is commonly detected in women up to 60 years, people with diabetes and in the elderly. It is not clear whether ...

Here we list specialized resources for other methods that Cochrane Groups have produced. Clinical study reports and other regulatory documents Clinical study reports (CSRs) are documents submitted to ...

Women who have immediate skin-to-skin contact with their newborns are probably more likely to exclusively breastfeed at hospital discharge and up to one month after birth (12 studies, 1556 ...

Myasthenia gravis is a rare disease where the immune system attacks the communication between nerves and muscles, causing weakness. It often affects the muscles used for eye movement, facial ...