Stay up to date here with the latest news and highlights from the Indianapolis Colts' Week 16 matchup on Monday Night Football against the San Francisco 49ers.

A meeting featuring two of the NFL's best in Christian McCaffrey and Jonathan Taylor will close Week 16 as the 49ers and Colts clash in a matchup with playoff implications.

Philip Rivers, the grandfather and former Pro Football Hall of Fame semifinalist, came out of retirement to play for the Indianapolis Colts.

The San Francisco 49ers didn’t play great, but they managed to snag a win in a game they needed to have to keep their spot in the NFC playoff picture.

Kyle Shanahan discusses the 49ers Week 15 win against the Tennessee Titans, sharing injury updates on WR Ricky Pearsall, and highlighting QB Brock Purdy and the offensive line unit.

Despite the Colts' blowout loss in Week 16, Philip Rivers turned back the clock a bit with some terrific throws in his second game since un-retiring. Here's a full breakdown of Rivers' numbers and highlights.

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are the highlights.

San Francisco 49ers legend Brent Jones met with the media to discuss his induction into the Edward J. DeBartolo Sr. 49ers Hall of Fame, his career highlights, and the relationships that defined his time with the franchise.

Brock Purdy threw a career-high five touchdown passes and Dee Winters returned an interception 74 yards for a score to lead the San Francisco 49ers to a 48-27 victory at Indianapolis