Louisville's backup running backup Duke Watson, for the second straight week, was designated as "out" on the first injury report after exiting the Virginia game three weeks ago. Starting defensive end Wesley Bailey, as well as rotational offensive lineman Naeer Jackson, were both listed as "questionable."

College football Week 9 odds, picks, predictions, TV channel, streaming for Boston College Eagles vs Louisville Cardinals ACC game Saturday, Oct. 25.

I’m tired, boss. The hard part of the schedule is finally here, and BC has a 1-6 record already. I’m tired already and it’s not going to get better. Louisville, Notre Dame, and Georgia Tech are all ranked opponents that remain on BC’s schedule.

LOUISVILLE, Ky. - On the heels of capturing one of their biggest road wins in program history, the Louisville program is returning home, where a matchup with Boston College is waiting for them. Kickoff from L&N Stadium is set for Saturday, Oct 25 at 7:30 p.m. EST.

Pregame analysis and predictions of the Boston College Eagles vs. Louisville Cardinals NCAAF game to be played on October 25, 2025 on ESPN.

Boston College heads to #19 Louisville (5-1, 2-1) for this week’s drubbing. The Cardinals are heavy favorites of more than three touchdowns over the struggling Eagles. Under head coach Jeff Brohm, Louisville aims to continue their strong start to the season,

Louisville football got a big Week 8 win over Miami. Can the Cards use that surging confidence against Boston College in Week 9?

The Cardinals knocked off No. 2 Miami last weekend, but Brohm has a history of following up big games with slip ups.